Graphical Abstract

Treatment of trifluoroacetamides sodium salt on α-hydroxy tosylate 1, or related compounds, afforded directly oxazolidinones 2 via trifluoromethyl elimination.

Graphical Abstract

Treatment of a quaternary 3-amino-5-nitrocollidinium salt with aqueous methylamine at room temperature leads to the formation of a nitroacetylpyrrole.

Graphical Abstract

Several primary aromatic amines have been converted to nitro compounds in good yields. The oxidant was oxone^® and the reactions were performed in 5 to 20% aqueous acetone and buffered with sodium bicarbonate.

Graphical Abstract

Treatment of N,N-unsaturated dialkyl-β-oxoamides by Mn(OAc)₃ leads to the formation of lactams .

Stereochemistry Abstract

C₁₀H₁₆OSi

Absolute configuration S

mp 43.0°C

[α]_D³⁰ −19.8 (c 0.59, CHCl₃)

source of chirality: enzymatic transesterification

E. e.=≥99% by chiral HPLC

C₁₂H₁₈O₂Si

Absolute configuration S

[α]_D²⁹ −53.6 (c 1.08, CHCl₃)

source of chirality: enzymatic transesterification

E. e.=≥99% by chiral HPLC

Graphical Abstract

Dimethyldioxirane readily oxidizes primary amines to nitro compounds.

Graphical Abstract

Aromatic cyclic ureas were synthesized in good yields from aromatic diamines by the reaction with carbon monoxide in the presence of selenium.

Graphical Abstract

Treatment of Cu(II) or Ni(II) porphyrins with 3-dimethylaminoacrolein/POCl₃ gives meso-(2-formylvinyl)porphyrins which can be cyclized in acid to give access to benzochlorins e.g.(5). Cu(II) or Ni(II) chlorins give benzoisobacteriochlorins e.g. (17) and/or benzobacteriochlorins e.g. (11). The (2-formylvinyl) compounds give dimers e.g. (21) upon reductive coupling.

Graphical Abstract

Aromatic amines (Scheme 1) and nitroaromatics (Scheme 2) was converted to the corresponding tertiary amine using decaborane.

Graphical Abstract

Aromatic primary amines, CuCN and an alkyl nitrite in DMSO yielded fair to moderate yields of the corresponding nitriles.

Graphical Abstract

Amides bonds are formed readily under mild conditions by the reaction of N-silylamines with the hydrolytically stable acyl fluorides.